GMDA (gene mutation analysis system),which is mainly used for analyzing ecological effects caused by pollutants in contaminated environment, is adapted to environmental science, environmental engineering, environmental microbiology, toxicology, molecular biology, immunology, cell biology, etc. Identification of mutations in specific genes has become an important strategy for diagnosis and prognosis of many diseases, including cancer. Several techniques, including DGGE, CDGE, TTGE, and SSCP, have been developed into specific methods to study mutant of heterogeneous tissue samples. These techniques can be used for rapidly screening dissimilar tissues, as well as each technology has its own function.

GMDA gene mutation analysis system consists of the electrophoresis equipment with temperature control module (including Chinese LCD microprocessor controlling heating, temperature range: 5-70 ℃) , the Chinese LCD programmable power supplies, buffer recirculation pumps, mixers, and accessories for special gel application. The cooling tank and the external laboratory cooler can control operating temperature to be at room temperature. a gel can run 56 samples in 2 hours , with accurate temperature control within 5-70 °C. It can be used to detect single base changes with the following electrophoretic techniques:

Single-strand conformation polymorphism (SSCP)
Denaturing gradient gel electrophoresis (DGGE)
Time, temperature gradient gel electrophoresis (TTGE)
Uniform denaturing gel electrophoresis (CDGE)

Technique data:

Experimental conditions can be accurately controlled to ensure the reliability and reproducibility of experimental results
System can run 56 samples in 2 hours, with accurate temperature control within 5-70 °C
Voltage range：0-300V, accuracy：0.1%, Current range：0-400mA, ripple factor：0.1%
Microcomputer intelligent control; Chinese LCD; with alarm devices to prevent over-voltage, over current, overload etc
Temperature control options, modular design, dedicated combination of accessories, simplified boot process

In order to obtain maximum throughput and efficiency, many laboratories adopt a variety of technologies. In fast-paced research environment, the rapid switching between different methods and the ability to switch to new technologies are critical. GMDA can meet all the needs for major mutation detection technology. Its flexible features and advantages include: temperature control options, modular design, dedicated combination of parts, simplified startup process, suitable for DGGE, CDGE, SSCP, and TTGE techniques.