Creative Animodel offers a complete set of DMPK analysis for our global clients, including in vivo and in vitro experiments. In the aspect of pharmacokinetic/pharmacodynamics (PK/PD) study, we provide normal animal models for PK/PD study as well as disease models such as chronic kidney disease and diabetes. Our central laboratory is fully equipped with the most advanced equipment, network and software infrastructure, outstanding technical support to ensure unparalleled services to our clients.
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Creative Animodel has collected more than 80 cases of human tumors. At present, 30 cases are growing as subcutaneous xenografts in nude mice, and others were retained as nitrogen frozen samples. Tumors types comprise: stomach, lung, liver, pancreas, kidney, bladder, skin, breast, brain, colon, prostate, sarcomas (bone), uterus, ovary and hematological models. Also, we have a full range of human tumor cell lines that have been validated in our in vivo efficacy studies or reported in literature. According to the requirements from clients and our experience, Creative Animodel can offer subcutaneous, orthotopic, metastatic, transgenic and chemo-induced models using these tumor samples and cell lines.
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