Based on our advanced technologies, Creative Animodel provides electrophysiological assays for characterization and screening of cardiac ion channel targets. Assays can be performed by manual or automated patch clamp. Stable cell lines are used, such as human atrial or ventricular myocytes, which express various ion channels or transient expression of ion channels.
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Creative Animodel has collected more than 80 cases of human tumors. At present, 30 cases are growing as subcutaneous xenografts in nude mice, and others were retained as nitrogen frozen samples. Tumors types comprise: stomach, lung, liver, pancreas, kidney, bladder, skin, breast, brain, colon, prostate, sarcomas (bone), uterus, ovary and hematological models. Also, we have a full range of human tumor cell lines that have been validated in our in vivo efficacy studies or reported in literature. According to the requirements from clients and our experience, Creative Animodel can offer subcutaneous, orthotopic, metastatic, transgenic and chemo-induced models using these tumor samples and cell lines.
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