Thank you for your interest in flexcell products

Bio Excellence international Tech Co.,Ltd has been acting as sole agent for the sale of flexcell products for more than ten years,Bio Excellence can provide free technical guidance for flexcell tension, compression, fluid shear products, user site installation as well as training, until the user can use them without limiting number of training times.If you have any questions, please do not hesitate to contact us.

flexcell Transwell Holder 6-Well

?Holders sit atop a 6-well Flexcell® Culture Plate (Fig. 1) and allow users to run co-culture or cell migration assays with standard transwells.

• Analyze cell migration in response to strain.
• Run experiments with unstrained control cells and the strained cells in the same culture plate well.
• Compatible with Transwells for 6-well plates. (See Corning's website for more information on Transwells.)

*6-well inserts with a 24 mm insert diameter or with a 37-41 mm outer lip diameter and 15.5-16.5 mm height.

Applications of Transwell® with Flexcell® Culture Plates

• Co-Culture - Culture two different cell types in the presence or absence of mechanical load. Isolate direct and auto/paracrine effects of mechanical load.
• Cell Migration - Examine the paracrine/autocrine effects of substrate strain on cell migration.
• Transport & Permeability - Examine drug transport in response to the paracrine effects of mechanical load.
• Cell Polarity - Analyze the formation of polarized layers of cells in response to the paracrine effects brought about by mechanical load. In addition, examine epithelial penetration by pathogens, wound repair, ion channel activity, and other processes that rely on well-differentiated polarized cell layers.
• Chemotaxis & Invasion - Analyze the effects of mechanical load on inflammatory cell migration, metastatic invasion, and angiogenesis.

Schematic of a Transwell Holder with a Transwell supported atop the rubber membrane in the well of BioFlex® culture plate.

flexcell Transwell Holder 24-Well

?Holders sit atop a 24-well Flexcell® Culture Plate (Fig. 1) and allow users to run co-culture or cell migration assays with standard transwells.

• Analyze cell migration in response to strain.
• Run experiments with unstrained control cells and the strained cells in the same culture plate well.
• Compatible with Transwells for 24-well plates. (See Corning's website for more information on Transwells.)

*24-well inserts with a 24 mm insert diameter or with a 37-41 mm outer lip diameter and 15.5-16.5 mm height.

Applications of Transwell® with Flexcell® Culture Plates

• Co-Culture - Culture two different cell types in the presence or absence of mechanical load. Isolate direct and auto/paracrine effects of mechanical load.
• Cell Migration - Examine the paracrine/autocrine effects of substrate strain on cell migration.
• Transport & Permeability - Examine drug transport in response to the paracrine effects of mechanical load.
• Cell Polarity - Analyze the formation of polarized layers of cells in response to the paracrine effects brought about by mechanical load. In addition, examine epithelial penetration by pathogens, wound repair, ion channel activity, and other processes that rely on well-differentiated polarized cell layers.
• Chemotaxis & Invasion - Analyze the effects of mechanical load on inflammatory cell migration, metastatic invasion, and angiogenesis.

Schematic of a Transwell Holder with a Transwell supported atop the rubber membrane in the well of BioFlex® culture plate.

Often work with flexcell tension system：

A computer-regulated bioreactor that uses vacuum pressure and positive air pressure to apply cyclic or static strain to cells cultured on flexible-bottomed culture plates.

• Applies a defined, controlled, static or cyclic deformation to cells growing in 3D or monolayer
• Allows users to simulate in vivo tissue strains and frequencies in vitro
• State-of-the-art digital valve automatically regulates vacuum pressure and positive air pressure for specified strain regimen
• Mimics in vivo conditions in cells from muscle, lung, heart, vascular vessels, skin, tendon, ligament, cartilage, and bone.
• FlexSoft® FX-6000™ software allows for multiple frequency, amplitude and waveform changes to be programmed in one regimen
• Compatible with Windows 10
• Use Bioflex® culture plates with cylindrical loading posts to apply equibiaxial strain
• Use Uniflex® culture plates with Arctangle® loading posts to apply uniaxial strain
• Gradient strain or unconstrained distention achieved by removing loading stations
• Drives up to 4 Flexlink® Controllers with 1 FX-6000T™ Tension System

• Available waveforms: static, sinusoidal, heart stimulation, triangular, square and custom