Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA XIII, also referred to as carbonate dehydratase XIII, is predominantly expressed in spleen, prostate, thymus, ovary, testis, colon and small intestine localizing to the cytoplasm. It exhibits highest homology with family members CA I, CA II and CA III. CA XIII may play a role in embryogenesis. Efficient inhibitors of CA XIII activity are sulfanilyl-sulfonamide type inhibitors.
CA XIII Polyclonal Antibody detects endogenous levels of CA XIII protein.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
CA XIII Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/ca-xiii-polyclonal-antibody-abp50816.
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