ChIP Validated Antibodies
The use of high quality and specific ChIP validated antibodies is essential for the success of a ChIP assay. The antibody must recognise and bind to native protein that is bound to DNA. Antibodies from other applications do not always work well in ChIP.
Mouse Anti‐RNA polymerase II CTD repeat YSPTSPS (phospho S)
Product Code : 700001
RNA polymerase II catalyzes the transcription of DNA into mRNA and other small nuclear RNAs in eukaryotes. It contains a CTD consisting of conserved heptapeptide repeats. Phosphorylation occurs at serine and therine residues located in the CTD repeats to activate the RNA pol II.
RNA pol II binds to several transcription factors in order to initiate transcription and therefore serves as an abundant antibody target for ChIP. This antibody recognises the C-terminal repeat of the largest subunit of RNA polymerase II. It recognises both unphosphorylated and phosphorylated form.
•Applications: ChIP, WB, ELISA, ICC, IP, Flow Cyt
•Source: Mouse
•Concentration:8mg/ml
•Type: Monoclonal
•Size: 100μl
•Purification: Protein A (affinity purified)
•Specificity: Mouse, Human, Saccharomyces cerevisiae, Arabidopsis thaliana, Caenorhabditis elegans, Fruit fly (Drosophila melanogaster), Schizososaccharomyces pombe, African Green Monkey
•Storage: -20°C (Avoid multiple free/thaw cycles as this may denature the antibody)
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