KIT encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT proto-oncogene receptor tyrosine kinase is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for KIT.
The Abbkine c-Kit (phospho Tyr721) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of c-Kit protein only when phosphorylated at Y721. The antibody has been validaed in WB, ELISA and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-c-Kit (phospho Tyr721) Polyclonal Antibody at https://www.abbkine.com/product/c-kit-phospho-tyr721-polyclonal-antibody-abp50290.
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