The protein (actin, alpha 2, smooth muscle, aorta) encoded by ACTA2 belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in ACTA2 cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.
The Abbkine α-Smooth Muscle Actin Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen and detects endogenous α-Smooth Muscle Actin protein. The antibody has been validaed in WB and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-α-Smooth Muscle Actin Polyclonal Antibody at https://www.abbkine.com/product/α-smooth-muscle-actin-polyclonal-antibody-abp50176.
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