Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H3A is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from HIST1H3A lack polyA tails; instead, they contain a palindromic termination element. HIST1H3A is found in the large histone gene cluster on chromosome 6p22-p21.3.
The Abbkine Histone H3 (Mono Methyl Lys79) Mouse Monoclonal Antibody (4C9) was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen and detects endogenous Histone H3 (mono methyl K79) protein. The antibody has been validaed in WB and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Mouse Anti-Histone H3 (Mono Methyl Lys79) Monoclonal Antibody (4C9) at https://www.abbkine.com/product/histone-h3-mono-methyl-lys79-monoclonal-antibody-4c9-abm40103.
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