Cleaved-Spectrin α II (D1185) Polyclonal Antibody,Abbkine Scientific Co.Ltd._specification/price/image

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Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. SPTAN1 encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. Spectrin alpha chain non-erythrocytic 1 has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in SPTAN1 are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.

The Abbkine Cleaved-Spectrin α II (D1185) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen anddetects endogenous levels of fragment of activated Spectrin α II protein resulting from cleavage adjacent to D1185. The antibody has been validaed in WB, ELISA and reacts with Human samples.

Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-Cleaved-Spectrin α II (D1185) Polyclonal Antibody at https://www.abbkine.com/product/cleaved-spectrin-α-ii-d1185-polyclonal-antibody-abp50054.

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.