C1R (Complement C1r Subcomponent) is a Protein Coding gene. Diseases associated with C1R include immunodeficiency due to an early component of complement deficiency and c1r/c1s deficiency, combined. Among its related pathways are Complement and coagulation cascades and Immune System. GO annotations related to C1R include calcium ion binding and serine-type peptidase activity. An important paralog of C1R is HP.C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.C1R aligns across a gap in the GRCh38 reference genome assembly, and therefore, the 5' end of C1R was annotated on NT_009714.18 and the 3' end was annotated on NT_009759.17 in NCBI's Homo sapiens Annotation Release 106.
The Abbkine Cleaved-C1r LC (I464) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen anddetects endogenous levels of fragment of activated C1r LC protein resulting from cleavage adjacent to I464. The antibody has been validaed in WB, ELISA and reacts with Human samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-Cleaved-C1r LC (I464) Polyclonal Antibody at https://www.abbkine.com/product/cleaved-c1r-lc-i464-polyclonal-antibody-abp50014.
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