ChIP Validated Antibodies
The use of high quality and specific ChIP validated antibodies is essential for the success of a ChIP assay. The antibody must recognise and bind to native protein that is bound to DNA. Antibodies from other applications do not always work well in ChIP.
Anti-Androgen Receptor (AR)
Product Code : 700008
The androgen receptor (AR) is a steroid hormone receptor involved in the signaling of testosterone. It is a regulatory gene that controls gene expression through binding to androgen receptor elements (AREs). The AR is associated with both normal prostate and cancerous prostate cell growth at abnormal levels of the gene (Lamb et al, 2014, BJUI). Androgens are also heavily involved in the pathogenesis of endometrial cancer (D.A. Gibson et al, 2014, Endocr Relat Cancer). DHT (dihydrotestosterone) is a natural androgen hormone that can activate the androgen receptor (Mostaghel, 2014, IJBS).
This antibody recognises peptide sequence at the N-terminus of AR of human origin.
•Applications: ChIP
•Source: Sheep
•Concentration: 1mg/ml
•Type: Polyclonal
•Size: 100μl
Purification: Protein G (affinity purified)
•Specificity: Human
•Storage: +2- +8°C (Do not freeze as this may denature the antibody)
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