Cell-based NAb assay designs utilize intracellular signaling events triggered by the drug candidates or the ligand inhibited by the drug candidates, and may also utilize study of extracellular binding events at the cell surface. The frequently-used readouts for Profacgen’s NAb cell based assays include: cell proliferation, biomarker, reporter gene expression, antibody- dependent cell-mediated cytotoxicity (ADCC), etc.
https://www.profacgen.com/Neutralizing-Antibody-NAb-Test-Service.htm
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