Animal models of schizophrenia at Creative Animodel serve for two main purposes. First, they may be heuristic, providing a framework in which to ask questions about etiology. Second, they may be predictive, i.e., used to test potential antipsychotic treatments, since animals and humans to a large extent share similar neuro-chemistries and neuro-circuitries of the brain.
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Creative Animodel has collected more than 80 cases of human tumors. At present, 30 cases are growing as subcutaneous xenografts in nude mice, and others were retained as nitrogen frozen samples. Tumors types comprise: stomach, lung, liver, pancreas, kidney, bladder, skin, breast, brain, colon, prostate, sarcomas (bone), uterus, ovary and hematological models. Also, we have a full range of human tumor cell lines that have been validated in our in vivo efficacy studies or reported in literature. According to the requirements from clients and our experience, Creative Animodel can offer subcutaneous, orthotopic, metastatic, transgenic and chemo-induced models using these tumor samples and cell lines.
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