Rituxan® (rituximab) is a genetically engineered chimeric murine/human monoclonal IgG1 kappa antibody directed against the CD20 antigen. Rituximab has an approximate molecular weight of 145 kD. Rituximab is produced by mammalian cell (Chinese Hamster Ovary) suspension culture in a nutrient medium containing the antibiotic gentamicin. Gentamicin is not detectable in the final product.
Rituximab is a sterile, clear, colorless, preservative-free liquid. Rituximab is supplied at a concentration of 10 mg/Ml, which contains polysorbate 80 (0.7 mg/mL), sodium chloride (9 mg/mL), sodium citrate dihydrate (7.35 mg/mL), and Water for Injection. The pH is 6.5.
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Name
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Rituximab
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CAS NO.
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174722-31-7
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Type
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Whole antibody
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Source
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Chimeric(mouse/human)
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Target
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CD20
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Clone
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Monoclone
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Formula
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C6416H9874N1688O1987S44
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Molecular Weight
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145 kDa
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Antibody Form
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Purified immunoglobulin
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Physical Form
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Solution
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Grade Standard
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Medicine Grade
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Place of Origin
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China(Mainland)
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Storage
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-70±15℃ for long-term storage, 2-8℃ for short-term storage, away from light.
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bio-equip.cn
中文
