Pembrolizumab biosimilar is a humanized monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. It is an IgG4 kappa immunoglobulin with an approximate molecular weight of 149 kDa.
Pembrolizumab biosimilar is supplied at a concentration of 25 mg/mL as a sterile, preservative-free, clear to slightly opalescent, colorless to slightly yellow solution, which contains 1.55 mg/mL L-histidine, 0.2 mg/mL polysorbate 80, 70 mg/mL sucrose, and Water for Injection.
Statement: this product is used for R&D only, not for clinical usage.
Name
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Pembrolizumab biosimilar
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CAS NO.
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1374853-91-4
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Type
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Whole antibody
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Source
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Humanized (from mouse)
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Target
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PD-1
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Clone
|
Monoclone
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Molecular Weight
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149 kDa
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Formula
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C6534H10004N1716O2036S46
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Antibody Form
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Purified immunoglobulin
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Physical Form
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Solution
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Grade Standard
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Medicine Grade
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Storage
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-70±15℃ for long-term storage, 2-8℃ for short-term storage, away from light.
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