TTC19 (Tetratricopeptide Repeat Domain 19) encodes a protein with a tetratricopeptide repeat (TPR) domain containing several TPRs of about 34 aa each. These repeats are found in a variety of organisms including bacteria, fungi and plants, and are involved in a variety of functions including protein-protein interactions. This protein is embedded in the inner mitochondrial membrane and is involved in the formation of the mitochondrial respiratory chain III. It has also been suggested that this protein plays a role in cytokinesis. Mutations in TTC19 cause mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for TTC19. TTC19 is a Protein Coding gene. Diseases associated with TTC19 include Mitochondrial Complex Iii Deficiency, Nuclear Type 2 and Mitochondrial Complex Iii Deficiency.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000 ELISA 1:5000-20000.
TTC19 Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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