Creative BioMart Expands Protein Extraction Capabilities to Support Life Science Research
Hits:27 Date: 4/28/2025
Creative BioMart, a biotechnology services provider, has recently updated its protein extraction service with improved protocols and quality control measures. The enhancements aim to address common challenges researchers face in obtaining high-quality protein samples for downstream applications.
Protein extraction is the process of separating proteins from biological samples (such as cells, tissues or microorganisms), and is a basic step in life science research and biotechnology applications. Its core goal is to obtain high-purity, structurally intact proteins while maintaining biological activity for subsequent experiments such as Western blot, mass spectrometry, enzyme activity assays or structural analysis.
Commonly used extraction methods include mechanical disruption (such as ultrasound, homogenization), chemical lysis (such as detergent dissolution) and enzymatic hydrolysis, and specific optimization schemes are required for different samples (mammalian cells, plant tissues, bacteria, etc.). The key challenges are to prevent protein degradation (requires low temperature operation and protease inhibitors), remove interfering substances such as nucleic acids/polysaccharides, and maintain the stability of insoluble proteins such as membrane proteins. Efficient protein extraction is crucial to experimental reproducibility and data reliability.
With cutting-edge tech and know-how, Creative BioMart now provides various methods to suit downstream analyses, delivering dependable, tailor-made solutions for both research and industrial uses. Types of samples can be handled by scientists at Creative BioMart, including animal tissues (brain, liver, muscle...), plant tissues (leaves, roots, stems...), cell line (primary cell, suspension cell...), and microorganisms (bacteria, fungi...).
The company employs multiple extraction methods, such as Ion-exchange, Gel filtration, Affinity (broad-spectrum), and Hydrophobic interaction, to accommodate different sample types and research requirements.
Creative BioMart provides a range of protein extraction services, including:
Membrane protein extraction
Creative BioMart can help extract a broad range of membrane proteins, such as GPCRs, ion channels, transporters, membrane enzymes, membrane fusion proteins.
Cytoplasmic protein extraction
Creative BioMart provides cytoplasmic proteins isolation and high-quality analysis to help obtain feady-to-use cytoplasmic proteins from various organisms.
Organelle protein extraction
Organelle isolation and purification: mitochondria, nucleus, chloroplasts, cell wall, and the plasma membrane.
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"Protein extraction is often the most variable step in experimental workflows," noted Linna, Chief Marketing Staff at Creative BioMart. "Our updated services focus on reproducibility and sample compatibility to help researchers obtain more consistent results."