Human Peroxidasin-like protein (PXDNL) ELISA Kit,Abbkine_specification/price/image

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PXDNL belongs to the peroxidase family. PXDNL is moderately expressed, only 28.6% of the average gene in this release, PXDNL contains 23 different gt-ag introns.XPO subfamily. Dysfunction of mitochondria in nerve cells contributes to the neurodegeneration of PD. When cells are infected by the CMV virus, they become resistant to certain mitochondrial toxins that may be important in causing PD. CMV-infected cells produce very high levels of a protein called PXDNL about which very little is known. PXDNL is selectively found in substantia nigra neurons, increasing its levels will detoxify the free radicals produced by malfunctioning mitochondria and thereby protect these neurons. PXDNL may protect against these toxic processes and, if so, it may open the way for a new approach to slowing or halting the progression of the disease.

Human Peroxidasin-like protein (PXDNL) ELISA Kit employs a two-site sandwich ELISA to quantitate PXDNL in samples. An antibody specific for PXDNL has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPXDNL present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PXDNL is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PXDNL bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Peroxidasin-like protein (PXDNL) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.