Human Caltrin (PYY2) ELISA Kit,Abbkine_specification/price/image

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NPY is an abundant neuropeptide regulating a wide range of physiologic activities. Another member of the NPY family, PYY, is an inhibitory hormone secreted by digestive tract endocrine cells. PPY is a pancreatic hormone inhibiting secretion of enzymes and bicarbonate from the exocrine pancreas. The genes encoding PYY and PPY are thought to have arisen by gene duplication and are localized on chromosome 17q21.1. All 3 genes contain 4 exons with little or no intronic homology. PYY2, like PYY1, has 4 exons and conserved 5-prime and 3-prime flanking sequences as well as conserved introns 2 and 3.Despite 92% identity between the PYY and PYY2 nucleotide sequences, PYY encodes a 98-amino acid protein and PYY2 encodes a 33-residue protein due to an alternative start site, as seen in bovine Pyy2 (seminalplasmin), and an early stop codon.

Human Caltrin (PYY2) ELISA Kit employs a two-site sandwich ELISA to quantitate PYY2 in samples. An antibody specific for PYY2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPYY2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PYY2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PYY2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Caltrin (PYY2) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/human-caltrin-pyy2-elisa-kit-kte61010/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.