Adrenergic receptors (ARs) include four general types that are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins.RAD54L2 (RAD54-like 2), also known as ARIP4, HSPC325 or SRISNF2L, is a 1,467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family that consists of one helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 is a DNA helicase that regulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. RAD54L2 is posttranslationally sumoylated or phosphorylated upon DNA damage.
Human Helicase ARIP4 (RAD54L2) ELISA Kit employs a two-site sandwich ELISA to quantitate RAD54L2 in samples. An antibody specific for RAD54L2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyRAD54L2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for RAD54L2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of RAD54L2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Human Helicase ARIP4 (RAD54L2) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/human-helicase-arip4-rad54l2-elisa-kit-kte60983/
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