Human Retinoic acid receptor responder protein 1 (RARRES1) ELISA Kit,Abbkine_specification/price/image

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RARRES1 was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.Strong RARRES1 expression could be induced by RAR-specific but not RXR-specific agents. In situ hybridization analysis showed that treatment of psoriatic rafts or patient skin lesions with tazarotene induces RARRES1 expression. Nonlesional and sham-treated lesional psoriatic skin showed no expression of RARRES1.

Human Retinoic acid receptor responder protein 1 (RARRES1) ELISA Kit employs a two-site sandwich ELISA to quantitate RARRES1 in samples. An antibody specific for RARRES1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyRARRES1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for RARRES1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of RARRES1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Retinoic acid receptor responder protein 1 (RARRES1) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/human-retinoic-acid-receptor-responder-protein-1-rarres1-elisa-kit-kte60975/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.