Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified.Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in nonmuscle cells.Defects in ACTG1 are the cause of non-syndromic sensorineural deafness autosomal dominant type 20 (DFNA20); also called autosomal dominant deafness type 26 (DFNA26).DFNA20 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
Human Actin, cytoplasmic 2 (ACTG1) ELISA Kit employs a two-site sandwich ELISA to quantitate ACTG1 in samples. An antibody specific for ACTG1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyACTG1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ACTG1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ACTG1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Human Actin, cytoplasmic 2 (ACTG1) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/human-actin-cytoplasmic-2-actg1-elisa-kit-kte60894/
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