ABCA13 is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
Human ATP-binding cassette sub-family A member 13 (ABCA13) ELISA Kit employs a two-site sandwich ELISA to quantitate ABCA13 in samples. An antibody specific for ABCA13 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyABCA13 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ABCA13 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ABCA13 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Human ATP-binding cassette sub-family A member 13 (ABCA13) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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