SCGB2A2 is member of the superfamily of secretoglobins, a group of small dimeric secreted and sometimes glycosylated proteins. Expressed mainly in mucosa, secretoglobins seems to be involved in cell signalling, immune response, chemotaxis, and could also serve as transporters for steroid hormones in humans. MGB1 encodes a deduced 93-amino acid protein with a 19-amino acid hydrophobic peptide signal sequence and a predicted molecular mass of 10.5-kD. The protein shares 42% sequence identity with the rat prostatein protein (rPSC3). It also shares high homology with rabbit and human uteroglobin (UGB) genes, including the conservation of cysteines known to play a role in disulfide bond formation between uteroglobin subunits and a conserved tyrosine required for progesterone binding to the uteroglobin dimer.
Human Mammaglobin-A (SCGB2A2) ELISA Kit employs a two-site sandwich ELISA to quantitate SCGB2A2 in samples. An antibody specific for SCGB2A2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySCGB2A2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SCGB2A2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SCGB2A2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Human Mammaglobin-A (SCGB2A2) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/human-mammaglobin-a-scgb2a2-elisa-kit-kte60739/
bio-equip.cn