Human P-selectin glycoprotein ligand 1 (SELPLG) ELISA Kit,Abbkine_specification/price/image

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SELPLG is the high affinity counter-receptor for P-selectin on myeloid cells and stimulated T lymphocytes. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. The organization of the SELPG gene closely resembles that of CD43 and the human platelet glycoprotein GpIb-alpha both of which have an intron in the 5-prime-noncoding region, a long second exon containing the complete coding region, and TATA-less promoters.P-selectin glycoprotein ligand-1 is a glycoprotein found on white blood cells and endothelial cells that binds to P-selectin (P stands for platelet). It is one of a family of selectins that includes E-selectin (endothelial) and L-selectin (leukocyte). PSGL-1 can bind to all three members of the family but binds best (with the highest affinity) to P-selectin.

Human P-selectin glycoprotein ligand 1 (SELPLG) ELISA Kit employs a two-site sandwich ELISA to quantitate SELPLG in samples. An antibody specific for SELPLG has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySELPLG present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SELPLG is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SELPLG bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human P-selectin glycoprotein ligand 1 (SELPLG) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/human-p-selectin-glycoprotein-ligand-1-selplg-elisa-kit-kte60718/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.