SYT11 is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Synaptotagmin-11 is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature.
Human Synaptotagmin-11 (SYT11) ELISA Kit employs a two-site sandwich ELISA to quantitate SYT11 in samples. An antibody specific for SYT11 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySYT11 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SYT11 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SYT11 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Human Synaptotagmin-11 (SYT11) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/human-synaptotagmin-11-syt11-elisa-kit-kte60426/
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