Human Steroidogenic acute regulatory protein, mitochondrial (STAR) ELISA Kit,Abbkine_specification/price/image

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The steroidogenic acute regulatory protein is a transport protein that regulates cholesterol transfer within the mitochondria, which is the rate-limiting step in the production of steroid hormones. It is primarily present in steroid-producing cells, including theca cells and luteal cells in the ovary, Leydig cells in the testis and cell types in the adrenal cortex. The domain of StAR important for promoting cholesterol transfer is the StAR-related transfer domain (START domain). StAR is the prototypic member of the START domain family of proteins and is thus also known as STARD1 for "START domain-containing protein 1". It is hypothesized that the START domain forms a pocket in StAR that binds single cholesterol molecules for delivery to P450scc.

Human Steroidogenic acute regulatory protein, mitochondrial (STAR) ELISA Kit employs a two-site sandwich ELISA to quantitate STAR in samples. An antibody specific for STAR has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySTAR present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for STAR is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of STAR bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Steroidogenic acute regulatory protein, mitochondrial (STAR) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/human-steroidogenic-acute-regulatory-protein-mitochondrial-star-elisa-kit-kte60374/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.