Human Suppressor of tumorigenicity 14 protein (ST14) ELISA Kit,Abbkine_specification/price/image

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ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. ST14 lacks a signal sequence and is likely to be a membrane-associated serine protease.Expression was also observed in a colorectal adenocarcinoma cell line, but not in several other cell lines tested.

Human Suppressor of tumorigenicity 14 protein (ST14) ELISA Kit employs a two-site sandwich ELISA to quantitate ST14 in samples. An antibody specific for ST14 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyST14 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ST14 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ST14 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Suppressor of tumorigenicity 14 protein (ST14) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/human-suppressor-of-tumorigenicity-14-protein-st14-elisa-kit-kte60373/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.