Tumor necrosis factor receptor superfamily, member 19 is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells.This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes.
Human Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) ELISA Kit employs a two-site sandwich ELISA to quantitate TNFRSF19 in samples. An antibody specific for TNFRSF19 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyTNFRSF19 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TNFRSF19 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TNFRSF19 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Human Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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