This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5 UTR, have been observed for this gene.
Human Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) ELISA Kit employs a two-site sandwich ELISA to quantitate TNFRSF6B in samples. An antibody specific for TNFRSF6B has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyTNFRSF6B present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TNFRSF6B is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TNFRSF6B bound in the initial step. The color development is stopped and the intensity of the color is measured.
Human Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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