SYNGR2 encodes an integral membrane protein containing four transmembrane regions and a C-terminal cytoplasmic tail that is tyrosine phosphorylated. The exact function of this protein is unclear, but studies of a similar rat protein suggest that it may play a role in regulating membrane traffic in non-neuronal cells.The gene belongs to the synaptogyrin gene family.Subcellular fractionation of rat brain cells indicated that both synaptogyrin and cellugyrin are associated with microsomes; however, only synaptogyrin is found in synaptic vesicles. The authors suggested that synaptogyrin is a specialized version of the ubiquitous cellugyrin, supporting the concept that synaptic vesicles are a simplified and specialized form of a generic trafficking organelle.
Bovine Synaptogyrin-2 (SYNGR2) ELISA Kit employs a two-site sandwich ELISA to quantitate SYNGR2 in samples. An antibody specific for SYNGR2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySYNGR2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SYNGR2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SYNGR2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Bovine Synaptogyrin-2 (SYNGR2) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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