YAP1 encodes a downstream nuclear effector (Yes associated protein 1) of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. YAP1 is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
The Abbkine YAP (phospho Ser127) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of YAP protein only when phosphorylated at S127. The antibody has been validaed in WB , IF, IHC-P, ELISA and reacts with Human, Mouse, Rat, Monkey samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-YAP (phospho Ser127) Polyclonal Antibody at https://www.abbkine.com/product/yap-phospho-ser127-polyclonal-antibody-abp50490.
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