SYK encodes a member of the family of non-receptor type Tyr protein kinases.Spleen associated tyrosine kinase is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for SYK.
The Abbkine Syk (phospho Tyr348) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of Syk protein only when phosphorylated at Y348. The antibody has been validaed in WB , IHC-P, ELISA and reacts with Human, Mouse, Rat, Monkey samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-Syk (phospho Tyr348) Polyclonal Antibody at https://www.abbkine.com/product/syk-phospho-tyr348-polyclonal-antibody-abp50481.
bio-equip.cn