PGR encodes a member of the steroid receptor superfamily. Progesterone receptor mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. PGR uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.
The Abbkine PR (phospho Ser190) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of PR protein only when phosphorylated at S190. The antibody has been validaed in WB, IHC-P, ELISA and reacts with Human, Monkey samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-PR (phospho Ser190) Polyclonal Antibody at https://www.abbkine.com/product/pr-phospho-ser190-polyclonal-antibody-abp50398.
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