RPS6KB1 encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. Ribosomal protein S6 kinase B1 responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of RPS6KB1 has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for RPS6KB1 on chromosome 17.
The Abbkine p70 S6 kinase α (phospho Thr229) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of p70 S6 kinase α protein only when phosphorylated at T229. The antibody has been validaed in WB, IHC-P, IF, ELISA and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-p70 S6 kinase α (phospho Thr229) Polyclonal Antibody at https://www.abbkine.com/product/p70-s6-kinase-α-phospho-thr229-polyclonal-antibody-abp50391.
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