Mitogen-activated protein kinase 1 encoded by MAP2K1 is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. Mitogen-activated protein kinase 1 lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway,Mitogen-activated protein kinase 1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
The Abbkine MEK-1/2 (phospho Ser218/222) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of MEK-1/2 protein only when phosphorylated at S218/222. The antibody has been validaed in WB, IHC-P, ELISA and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-MEK-1/2 (phospho Ser218/222) Polyclonal Antibody at https://www.abbkine.com/product/mek-1-2-phospho-ser218-222-polyclonal-antibody-abp50356.
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