G3BP1 encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme (G3BP stress granule assembly factor 1) is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of G3BP1 have been described, but the full-length nature of some of these variants has not been determined.
The Abbkine G3BP1 (phospho Ser232) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of G3BP1 protein only when phosphorylated at S232. The antibody has been validaed in WB, IHC-P, ELISA and reacts with Human, Mouse samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-G3BP1 (phospho Ser232) Polyclonal Antibody at https://www.abbkine.com/product/g3bp1-phospho-ser232-polyclonal-antibody-abp50318.
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