ERBIN is a member of the leucine-rich repeat and PDZ domain (LAP) family.Erbb2 interacting protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for ERBIN.
The Abbkine Erbin (phospho Tyr1104) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of Erbin protein only when phosphorylated at Y1104. The antibody has been validaed in WB, ELISA and reacts with Human samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-Erbin (phospho Tyr1104) Polyclonal Antibody at https://www.abbkine.com/product/erbin-phospho-tyr1104-polyclonal-antibody-abp50308.
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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.