EPHA2 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA2 encodes EPH receptor A2 that binds ephrin-A ligands. Mutations in EPHA2 are the cause of certain genetically-related cataract disorders.
The Abbkine EphA2 (phospho Tyr588) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of EphA2 protein only when phosphorylated at Y588. The antibody has been validaed in WB, ELISA and reacts with Human, Mouse samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-EphA2 (phospho Tyr588) Polyclonal Antibody at https://www.abbkine.com/product/epha2-phospho-tyr588-polyclonal-antibody-abp50307.
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