PPP1R1B encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, PPP1R1B may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for PPP1R1B.
The Abbkine DARPP-32 (phospho Thr75) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of DARPP-32 protein only when phosphorylated at T75. The antibody has been validaed in WB, IHC-P, ELISA and reacts with Human, Mouse, Rat, Monkey samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-DARPP-32 (phospho Thr75) Polyclonal Antibody at https://www.abbkine.com/product/darpp-32-phospho-thr75-polyclonal-antibody-abp50298.
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