SRC is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC proto-oncogene, non-receptor tyrosine kinase encoded by SRC is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in SRC could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for SRC.
The Abbkine c-Src (phospho Tyr529) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of c-Src protein only when phosphorylated at Y529. The antibody has been validaed in WB, IHC-P, ELISA and reacts with Human, Mouse, Rat, Monkey samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-c-Src (phospho Tyr529) Polyclonal Antibody at https://www.abbkine.com/product/c-src-phospho-tyr529-polyclonal-antibody-abp50294.
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