ChIP Validated Antibodies
The use of high quality and specific ChIP validated antibodies is essential for the success of a ChIP assay. The antibody must recognise and bind to native protein that is bound to DNA. Antibodies from other applications do not always work well in ChIP.
Anti H3K27ac, Clone RM172
Product Code : 700011
Histone 3 (H3) is one of the core histone proteins, comprising the protein component of chromatin. H3 is ubiquitous within chromosomes and can be found bound to most gene sequences throughout the genome. Acetylation of histone H3 occurs at several different lysine positions on the histone tail and is catalysed by a group of enzymes called histone acetyltransferases (HATs). The acetylation of lysine 27 on histone 3 can be used to identify active enhancer sites, separating them from poised enhancers. Histone acetylation is associated with active transcription through its roles in chromatin remodelling and gene activation.
This antibody recognises an acetyl-peptide corresponding to the Acetyl-Histone H3 (Lys 27).
•Applications: ChIP, WB, ELISA, Multiplex
•Source: Rabbit
•Concentration: 1mg/ml
•Type: Monoclonal
•Size: 100μl
•Purification: Protein A (affinity purified)
•Specificity: Human
•Storage: +2- +8°C
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