SBC is the first affymetrix Authorised service provider in China.We has built our infrastructure to facilitate the use of microarray technology in preclinical studies and clinical trials and to generate data in a suitable format for regulatory submissions. Leaded by Ph.D. molecular biologists and technical staff with more than 20 years combined industry experience, the center has hybridized and analyzed ten of thousands of Affymetrix Gene Chips and provided microarray servics and solutions for experimental design, sample preparation, sample processing, data analysis and data submission .
Service and Data Quality
1. SBC has developed and implemented specific SOPs that not only describe all procedures in the laboratory pertaining to microarray testing, but that also stipulate the mechanism by which laboratory associates are qualified and trained, how instruments are validated and maintained, as well as how reagents are ordered and validated before use.
2. To generate highest quality of data, SBC use stringent quantitative and qualitative quality control metrics ensure consistency and quality.
Chain of Custody
SBC meet the rigorous specimen logistics requirements associated with clinical trials though our central laboratory service to provide validated chain-of-custody for these critical samples.
Formalin-Fixed Paraffin-Embedded Samples (FFPE)
As the exclusive partner of Response Genetics, Inc (RGI) in China, we provide the only FFPE sample service in China. We employ RGI��s ��leading-edge�� tools to extract sufficient RNA from FFPE tissues for successful gene expression analysis .RGI patented procedure is extensively validated for its reproducibility, sensitivity and exportability
Preclinical studies and Clinical Trials References
With enhanced quality services and extensive documentation for eventual regulatory submissions, SBC has been selected by worldwide biotech/pharmaceutical industry as their microarray service provider. SBC has provided service to 3 of the top 5 pharmaceutical companies
Data Validation and Alternative Platforms
SBC have capability to perform genomic expression assays using several complementary technologies, including the following platforms:
1. Applied Biosystems - TaqMan assays for real-time PCR
2. Illumina- As the largest illumina service center in China, we provide whole genome and focus gene set profiling using Sentrix Array Matrices and Sentrix BeadChips
3. Agilent- genome-wide profiling of genomic aberrations using aCGH platform ; Genome expression profiling using microarray platform
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SBC Expression Analysis Services:
FFPE Sample Service (excllusive in China)
Affymetrix Platform:Affymetrix Genechip Expression Analysis
Illumina platform: whole genome profiling with Sentrix Array Matrices/Focus Gene sets Profiling with Sentrix BeadChips
Agilent platform:Genome expression profiling/ genome-wide profiling of genomic aberrations using aCGH platform
ABI PlatformI:TaqMan assays for real-time PCR
SBC Pharmacogenomics Sercives:
Illumina Platform:Whole genome SNP genotyping with Infinium assay Focused SNP genotyping with custom or standard golden gate assay/ Methylation profiling with golden gate standard or custom assay
Affymetrix Platform:Whole genome SNP Genotyping with Affymetrix GeneChip/Focused SNP genotyping with Affymetrix GeneChip Application-Specific Fixed Assays/Roche AmpliChip? CYP450 Service
Beckman Platform:Beckman SNPsteam Service
ABI Platfrom: ABI Genotyping with ABI Taqman assay/ DNA Sequencing service with ABI 3730xl
SBC Central Laboratory Services:
Leading Central Laboratory Services provider in China. Key features includes:Advanced Project ,Management,IT support,Professional Logistics,Fully Owned Facilities.
Tissure Bank and TMA Services:
One of the largest Tissue Bank in China,Providing more than 10000 spicemans including most common cancers and nomal tissues
SBC RepairChip Service:
Innovative Systems Biological tools to facilitate drug discovery.
China Headquater
Shanghai Biochip Co., Ltd.(SBC)
No.151,Libing Rd.,Zhangjiang Hi-Tech Park,Pudong,Shanghai,201203
Fax:86-21-51320266 Tel 86-21-51320288
Toll-free:800-820-5086
E-mail marketing@shanghaibio.com
http://www.shbiochip.com/en