The PS3™ is a simple, low-cost solution to your peptide synthesis needs. The PS3™ has 3 serial reaction vessels and allows up to 45 couplings without user intervention or reloading. The efficient packaging method for protected amino acids and activator simplifies procedures and reduces the number of mechanical components required. The resulting synthesizer is reliable, versatile, efficient, highly productive and low cost. It is also easy to use, permitting laboratory personnel to synthesize peptides with minimal training.
Features：
Simple
Load vials in sequence. Indicate start and stop positions. Specify standard or custom program for each coupling, and push "RUN."
Fast
Typical cycle times are under 40 minutes per coupling. Three reaction vessels let you synthesize up to three peptides without operator attention.
Flexible
The PS3™ allows you to use a variety of coupling techniques: Fmoc-N-carboxyanhydride and Fmoc-acid fluoride chemistries can be performed without instrument modification. Different chemistries can be mixed in one synthesis.
The PS3™ can also be used with either Fmoc or t-Boc protected amino acids. Pre-packaged reagents are available for 0.1 and 0.5 mmol synthesis scales. Coupling programs can be customized for special need.s
Reliable
The zero-dead-volume fluid valve system has all PTFE wetted surfaces and just one moving part. A self-diagnostic program and multiple sensors ensure proper performance while a printer provides a permanent record of each synthesis
High Productivity
The PS3™ will perform up to 45 couplings automatically, without reloading or user intervention. With three reaction vessels, the PS3™ can synthesize three completely different peptides sequentially. Set it up to run overnight or over a weekend, for maximum productivity!
Inert Atmosphere
Fluid transfer and mixing are accomplished under inert atmospheres of nitrogen or argon.
Specifications：
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Synthesis Scale:
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0.005 - 1.50 mmol (at 2x excess, up to 1.0 g of resin per RV) |
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Unattended Couplings:
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45 |
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Reaction Vessels:
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Three, glass (2 × 30mL; 1 × 75 mL) |
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Reagents/Solvents:
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Amino acids & activators:
Prepackaged vials (0.4 mmol and 1.0 mmol)
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for F-MOC:
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20% Piperidine/DMF: Prepackaged bottles (1L)
0.4M N-Methylmorpholine/DMF:
Prepackaged bottles (1L)
Dimethylformamide or NMP: Bottles (2 × 4L) |
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for t-BOC:
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50% TFA in methylene chloride (1L)
10% diisopropylethylamine in DMF (1L)
Methylene chloride (2 × 4L) |
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Fluid Transfer:
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Nitrogen or Argon pressure |
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Solution Removal:
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Filtration |
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Instrument Display:
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LCD |
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Printer:
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Panasonic Model KX-P023 |
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Printer Interface:
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RS232 |
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Power:
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105-125/210-250 volts, 50/60 Hz |
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Dimensions:
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32 inch Wide x 30 inch Height x 29 inch Depth
(81.3 cm W x 49 cm H x 51 cm D) |
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Weight:
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Approximately 50 lbs (23 kg) |
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