Rat Prokineticin receptor 1 (PROKR1) ELISA Kit,Abbkine_specification/price/image

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The prokineticin receptor is a G-protein coupled receptor which binds the peptide hormone prokineticin. These receptors mediate gastrointestinal smooth muscle contraction and angiogenesis. There are two variants each encoded by a different gene. Prokineticin receptor 1 (also known as PKR1, or GPR73A), is encoded by the PROKR1 gene. GPR73A is a receptor for prokineticin 1. It is a member of the GPCR family and is coupled to the G(q) subclass of heteromeric G proteins. Activation of the receptor leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. GPR73A expression has been reported in adrenal, peripheral blood leukocytes, brain, colon, pancreas, prostate, rectum, salivary gland, small intestine, spleen, stomach, testis, and thyroid.

Rat Prokineticin receptor 1 (PROKR1) ELISA Kit employs a two-site sandwich ELISA to quantitate PROKR1 in samples. An antibody specific for PROKR1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPROKR1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PROKR1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PROKR1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Rat Prokineticin receptor 1 (PROKR1) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.