Rat NAD-dependent deacetylase sirtuin-2 (SIRT2) ELISA Kit,Abbkine_specification/price/image

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Sirtuin 2(silent mating type information regulation 2 homolog) 2 (S. cerevisiae), also known as SIRT2, is a human gene.This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two transcript variants result from alternative splicing of this gene.

Rat NAD-dependent deacetylase sirtuin-2 (SIRT2) ELISA Kit employs a two-site sandwich ELISA to quantitate SIRT2 in samples. An antibody specific for SIRT2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySIRT2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SIRT2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SIRT2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Rat NAD-dependent deacetylase sirtuin-2 (SIRT2) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.