FGF15 is the mouse ortholog of human FGF19 (hence there is no human FGF15).Fibroblast growth factors, or FGFs, are a family of growth factors involved in angiogenesis, wound healing, and embryonic development. The FGFs are heparin-binding proteins and interactions with cell-surface associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs are key players in the processes of proliferation and differentiation of wide variety of cells and tissues.Fibroblast growth factor was found in pituitary extracts by Armelin in 1973 and then was also found in a cow brain extract by Gospodarowicz et al. and tested in a bioassay which caused fibroblasts to proliferate (first published report in 1974).
Mouse Fibroblast Growth Factor 15 (FGF15) ELISA Kit employs a two-site sandwich ELISA to quantitate FGF15 in samples. An antibody specific for FGF15 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyFGF15 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for FGF15 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of FGF15 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Mouse Fibroblast Growth Factor 15 (FGF15) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/mouse-fibroblast-growth-factor-15-fgf15-elisa-kit-kte71576/
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