Mouse Dermatopontin antibody (DPT-Ab) ELISA Kit,Abbkine_specification/price/image

Product Detail
Company Profile

Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin. Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts.

Mouse Dermatopontin antibody (DPT-Ab) ELISA Kit employs a two-site sandwich ELISA to quantitate DPT-Ab in samples. An antibody specific for DPT-Ab has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyDPT-Ab present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for DPT-Ab is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of DPT-Ab bound in the initial step. The color development is stopped and the intensity of the color is measured.

Mouse Dermatopontin antibody (DPT-Ab) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/mouse-dermatopontin-antibody-dpt-ab-elisa-kit-kte71516/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.