Human Dynein heavy chain domain-containing protein 1 (DNHD1) ELISA Kit,Abbkine_specification/price/image

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DNHD1 Belongs to the dynein heavy chain family. Dynein was first isolated from Tetrahymena cilia four decades ago. The analysis of the primary structure of the dynein heavy chain and the discovery that many organisms express multiple dynein heavy chains have led to two insights. One, dynein, whose motor domain comprises six AAA modules and two potential mechanical levers, generates movement by a mechanism that is fundamentally different than that which underlies the motion of myosin and kinesin. And two, organisms with cilia or flagella express approximately 14 different dynein heavy chain genes, each gene encodes a distinct dynein protein isoform, and each isoform appears to be functionally specialized. Sequence comparisons demonstrate that functionally equivalent isoforms of dynein heavy chains are well conserved across species.

Human Dynein heavy chain domain-containing protein 1 (DNHD1) ELISA Kit employs a two-site sandwich ELISA to quantitate DNHD1 in samples. An antibody specific for DNHD1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyDNHD1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for DNHD1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of DNHD1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Dynein heavy chain domain-containing protein 1 (DNHD1) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/human-dynein-heavy-chain-domain-containing-protein-1-dnhd1-elisa-kit-kte61996/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.